Today, tutorial researchers profit from the modifications pushed by digital applied sciences and the large progress of information and knowledge, on globalisation, enlargement of the scientific neighborhood, and the linkage between totally different scientific communities and the society. To totally profit from this improvement, nevertheless, data wants to be shared overtly and transparently. Digitalisation performs a significant position right here as a result of it permeates all areas of enterprise, science and society and is among the key drivers for innovation and worldwide cooperation.
To handle the ensuing alternatives, the EU promotes the event and use of collaborative methods to produce and share information and knowledge as early as attainable in the research course of, but additionally to appropriately safe outcomes with the European technique for Open Science (OS). It is now broadly recognised that making research outcomes extra accessible to all societal actors contributes to simpler and environment friendly science; it additionally serves as a lift for innovation in the general public and personal sectors. However for research knowledge to be findable, accessible, interoperable and reusable using requirements is crucial. At the metadata stage, appreciable efforts in standardisation have already been made (e.g. Data Management Plan and FAIR Principle and so forth.)
whereas in context with the uncooked knowledge these elementary efforts are nonetheless fragmented and in some circumstances utterly lacking. The CHARME consortium, funded by the European Cooperation in Science and Technology (COST) Agency, has recognized wants and gaps in the sphere of standardisation in the life sciences and additionally mentioned potential hurdles for implementation of requirements in present observe. Here, the authors recommend 4 measures in response to present challenges to guarantee a top quality of life science research knowledge and their re-usability for research and innovation.
Category principle and foundations of life science: A structuralist perspective on cognition
Category principle has lately been utilized efficiently past arithmetic and its foundations, for instance, in quantum physics, quantum computing, linguistics, and pure language processing in synthetic intelligence. Category principle right this moment is arguably foundations of science in addition to foundations of arithmetic. Yet functions of class principle to the life sciences are nonetheless restricted, and there are seemingly no clearly profitable paradigmatic circumstances of them. Here we handle foundational elements of class principle in and throughout the sciences, and potential structural interconnections between class principle and the life sciences, in explicit cognitive science.
More particularly, we first handle the 2 elements of class principle as foundations of science and as foundations of arithmetic in explicit, and then talk about what class principle may do for foundations of life science, in explicit cognitive science. We suggest, amongst different issues, a categorical structuralist approach to the thoughts-physique drawback as an various to reductionist approaches, which is arguably of each scientific and metaphysical significance on the identical time.
Category principle permits us to elucidate structural interconnections between the legal guidelines of cognition and the legal guidelines of actuality, thus paving the way in which for overcoming the Cartesian dualism separating the cognitive and bodily worlds. Put one other approach, class principle means that there could also be larger legal guidelines governing each worlds directly; the upper structuralist principle of cognition might embody the double side principle of data by David Chalmers.
Journal publication ethics and implications for life science researchers: a COPE perspective
The high quality of the research report in the type of peer-reviewed journal archives is a mirrored image of not solely the standard of the research publication and correction course of, but additionally the standard of the underlying information creation course of. Key to the integrity of the research report are honesty and accountability from all events concerned in governing, performing, and publishing scholarly work. A concerted effort is required to nurture an moral research publishing tradition by selling moral observe, related coaching, and efficient methods for responding to allegations of research or publication misconduct.
The Committee on Publication Ethics (COPE) is a membership organisation that goals to promote integrity in research publishing, for instance, by growing and encouraging greatest practices to be certain that research is reported ethically, utterly, and transparently. COPE makes use of the Principles of Transparency and Best Practice in Scholarly Publishing as a part of its standards when evaluating publishers and journals as members. Researchers may make use of those tips to assess a journal’s high quality and to acquire insights into what peer-reviewed journals anticipate from authors.
) ELISA kit for HIS (Histamine) |
|
E-EL-0032 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 377 |
- Gentaur's HIS ELISA kit utilizes the Competitive-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with HIS. During the reaction, HIS in the sample or standard competes with a fixed amount of HIS on the solid phase suppo
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|
|
Description: A competitive ELISA kit for quantitative measurement of HIS (Histamine) in samples from Serum, Plasma, Cell supernatant |
 ELISA kit for General Histamine |
|
EK2448 |
SAB |
96 tests |
EUR 603 |
|
Description: Enzyme-linked immunosorbent assay kit for quantification of General Histamine in samples from serum, plasma, tissue homogenates and other biological fluids. |
 ELISA kit for Human Histamine |
|
KTE62938-48T |
Abbkine |
48T |
EUR 354 |
|
Description: Quantitative sandwich ELISA for measuring Human Histamine in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
|
ELISA kit for Human Histamine |
|
KTE62938-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2252 |
|
Description: Quantitative sandwich ELISA for measuring Human Histamine in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
|
ELISA kit for Human Histamine |
|
KTE62938-96T |
Abbkine |
96T |
EUR 572 |
|
Description: Quantitative sandwich ELISA for measuring Human Histamine in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
 ELISA kit for Rat Histamine |
|
KTE101102-48T |
Abbkine |
48T |
EUR 354 |
|
Description: Quantitative sandwich ELISA for measuring Rat Histamine in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
|
ELISA kit for Rat Histamine |
|
KTE101102-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2252 |
|
Description: Quantitative sandwich ELISA for measuring Rat Histamine in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
|
ELISA kit for Rat Histamine |
|
KTE101102-96T |
Abbkine |
96T |
EUR 572 |
|
Description: Quantitative sandwich ELISA for measuring Rat Histamine in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
 ELISA kit for Mouse Histamine |
|
KTE71604-48T |
Abbkine |
48T |
EUR 354 |
|
Description: Quantitative sandwich ELISA for measuring Mouse Histamine in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
|
ELISA kit for Mouse Histamine |
|
KTE71604-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2252 |
|
Description: Quantitative sandwich ELISA for measuring Mouse Histamine in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
|
ELISA kit for Mouse Histamine |
|
KTE71604-96T |
Abbkine |
96T |
EUR 572 |
|
Description: Quantitative sandwich ELISA for measuring Mouse Histamine in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
 Histamine |
|
20-abx182483 |
Abbexa |
-
EUR 829.00
-
EUR 258.00
-
EUR 551.00
|
|
- Shipped within 1-2 weeks.
|
|
Histamine |
|
HB0500 |
Bio Basic |
1g |
EUR 126.56 |
- Product category: Biochemicals/Amino Acids/Derivatives
|
) ELISA kit for General HA (Histamine) |
|
ELK7869 |
ELK Biotech |
1 plate of 96 wells |
EUR 372 |
- A monoclonal antibody specific to Histamine (HA) has been pre-coated onto a microplate. A competitive inhibition reaction is launched between biotin labeled Histamine (HA) and unlabeled Histamine (HA) (Standards or samples) with the pre-coated antibo
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|
|
Description: A competitive Inhibition ELISA kit for detection of Histamine from General in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
|
ELISA kit for General HA (Histamine) |
|
ELK8094 |
ELK Biotech |
1 plate of 96 wells |
EUR 372 |
- A monoclonal antibody specific to Hyaluronic Acid (HA) has been pre-coated onto a microplate. A competitive inhibition reaction is launched between biotin labeled Hyaluronic Acid (HA) and unlabeled Hyaluronic Acid (HA) (Standards or samples) with the
- Show more
|
|
Description: A competitive Inhibition ELISA kit for detection of Histamine from General in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
 Histamine antibody |
|
20R-HR017 |
Fitzgerald |
50 uL |
EUR 918 |
|
Description: Rabbit polyclonal Histamine antibody |
 Histamine 2HCl |
|
B1561-5.1 |
ApexBio |
10 mM (in 1mL DMSO) |
EUR 108 |
|
Description: Histamine is an organic nitrogen compound, acts on target cells in mammalian brain via stimulation of Histamine 1/2. |
|
Histamine 2HCl |
|
B1561-50 |
ApexBio |
50 mg |
EUR 128 |
|
Description: Histamine is an organic nitrogen compound, acts on target cells in mammalian brain via stimulation of Histamine 1/2. |
|
Histamine 2HCl |
|
B1561-S |
ApexBio |
Evaluation Sample |
EUR 81 |
|
Description: Histamine is an organic nitrogen compound, acts on target cells in mammalian brain via stimulation of Histamine 1/2. |
 Histamine Phosphate |
|
B1770-5.1 |
ApexBio |
10 mM (in 1mL DMSO) |
EUR 108 |
|
Description: Histamine acts directly on the blood vessels to dilate arteries and capillaries mediated by both H 1- and H 2-receptors. |
|
Histamine Phosphate |
|
B1770-50 |
ApexBio |
50 mg |
EUR 128 |
|
Description: Histamine acts directly on the blood vessels to dilate arteries and capillaries mediated by both H 1- and H 2-receptors. |
 Histamine-BSA |
|
80-1460 |
Fitzgerald |
1 mg |
EUR 349 |
|
Description: BSA conjugated Histamine Hapten |
 Histamine-OVA |
|
80-1461 |
Fitzgerald |
1 mg |
EUR 349 |
|
Description: OVA conjugated Histamine Hapten |
|
Histamine-OVA |
|
80-1462 |
Fitzgerald |
1 mg |
EUR 349 |
|
Description: OVA conjugated Histamine Hapten |
) Histamine (BSA) |
|
20-abx165751 |
Abbexa |
-
EUR 551.00
-
EUR 244.00
-
EUR 1595.00
-
EUR 648.00
-
EUR 411.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
- Shipped within 5-7 working days.
|
) Histamine (OVA) |
|
20-abx165752 |
Abbexa |
-
EUR 551.00
-
EUR 244.00
-
EUR 1595.00
-
EUR 648.00
-
EUR 411.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
- Shipped within 5-7 working days.
|
 Histamine diphosphate |
|
HB0502 |
Bio Basic |
5g |
EUR 63.92 |
- Product category: Biochemicals/Misc. Biochemicals
|
 Vatalanib Dihydrochloride |
|
2025-25 |
Biovision |
|
EUR 305 |
|
Vatalanib Dihydrochloride |
|
2025-5 |
Biovision |
|
EUR 126 |
 1400W dihydrochloride |
|
2055-25 |
Biovision |
|
EUR 338 |
|
1400W dihydrochloride |
|
2055-5 |
Biovision |
|
EUR 126 |
 Norquetiapine dihydrochloride |
|
2362-250 |
Biovision |
|
EUR 414 |
|
Norquetiapine dihydrochloride |
|
2362-50 |
Biovision |
|
EUR 142 |
 Berbamine dihydrochloride |
|
2520-100 |
Biovision |
|
EUR 131 |
|
Berbamine dihydrochloride |
|
2520-500 |
Biovision |
|
EUR 370 |
 Antipain dihydrochloride |
|
2834-25 |
Biovision |
|
EUR 327 |
|
Antipain dihydrochloride |
|
2834-5 |
Biovision |
|
EUR 120 |
 Dorsmorphin dihydrochloride |
|
2835-25 |
Biovision |
|
EUR 588 |
|
Dorsmorphin dihydrochloride |
|
2835-5 |
Biovision |
|
EUR 185 |
 GGACK Dihydrochloride |
|
1847-5 |
Biovision |
5 mg |
EUR 319 |
- Frequently asked questions for this product: Is the GGACK Dihydrochloride cell-permeable? - No
- Is this item a salt form of GGACK Dihydrochloride? - Yes
- Does this product have/require an MSDS? - Yes
- What is the biological function of this molecul
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|
|
Description: A potent and irreversible inhibitor of Urokinase (uPA (IC??<1 µM), Factor VIIa, Factor IXa, Factor Xa, and trypsin. |
 PPACK Dihydrochloride |
|
1848-5 |
Biovision |
|
EUR 251 |
 Puromycin Dihydrochloride |
|
1860-100 |
Biovision |
|
EUR 272 |
|
Puromycin Dihydrochloride |
|
1860-1000 |
Biovision |
|
EUR 1295 |
|
Puromycin Dihydrochloride |
|
1860-25 |
Biovision |
|
EUR 126 |
|
Puromycin Dihydrochloride |
|
1860-250 |
Biovision |
|
EUR 457 |
|
Puromycin Dihydrochloride |
|
1860-500 |
Biovision |
|
EUR 805 |
 Emetine dihydrochloride |
|
1970-250 |
Biovision |
|
EUR 359 |
|
Emetine dihydrochloride |
|
1970-50 |
Biovision |
|
EUR 137 |
 Dexpramipexole dihydrochloride |
|
B2215-25 |
Biovision |
|
EUR 457 |
|
Dexpramipexole dihydrochloride |
|
B2215-5 |
Biovision |
|
EUR 153 |
 Daclatasvir dihydrochloride |
|
B2224-25 |
Biovision |
|
EUR 414 |
|
Daclatasvir dihydrochloride |
|
B2224-5 |
Biovision |
|
EUR 142 |
 Netarsudil dihydrochloride |
|
B2387-25 |
Biovision |
|
EUR 457 |
|
Netarsudil dihydrochloride |
|
B2387-5 |
Biovision |
|
EUR 153 |
 Furamidine dihydrochloride |
|
B2581-25 |
Biovision |
|
EUR 544 |
|
Furamidine dihydrochloride |
|
B2581-5 |
Biovision |
|
EUR 175 |
 Vanoxerine dihydrochloride |
|
B3248-10 |
ApexBio |
10 mg |
EUR 118 |
|
Description: Vanoxerine is an antagonist of dopamine transporter (DAT1) with Ki value of 16.9nM [1].As an antagonist of DAT, vanoxerine is developed for treatment of Parkinson's disease and depression but has no effect on these diseases. |
|
Vanoxerine dihydrochloride |
|
B3248-25 |
ApexBio |
25 mg |
EUR 210 |
|
Description: Vanoxerine is an antagonist of dopamine transporter (DAT1) with Ki value of 16.9nM [1].As an antagonist of DAT, vanoxerine is developed for treatment of Parkinson's disease and depression but has no effect on these diseases. |
|
Vanoxerine dihydrochloride |
|
B3248-50 |
ApexBio |
50 mg |
EUR 332 |
|
Description: Vanoxerine is an antagonist of dopamine transporter (DAT1) with Ki value of 16.9nM [1].As an antagonist of DAT, vanoxerine is developed for treatment of Parkinson's disease and depression but has no effect on these diseases. |
 Spectinomycin dihydrochloride |
|
B3342-1000 |
ApexBio |
1 g |
EUR 150 |
|
Description: Spectinomycin Dihydrochloride is a new parenteral antibiotic prepared from Streptomyces spectabilis. |
|
Spectinomycin dihydrochloride |
|
B3342-5.1 |
ApexBio |
10 mM (in 1mL H2O) |
EUR 168 |
|
Description: Spectinomycin Dihydrochloride is a new parenteral antibiotic prepared from Streptomyces spectabilis. |
|
Spectinomycin dihydrochloride |
|
B3342-5000 |
ApexBio |
5 g |
EUR 283 |
|
Description: Spectinomycin Dihydrochloride is a new parenteral antibiotic prepared from Streptomyces spectabilis. |
 Pentamidine dihydrochloride |
|
B3416-50 |
ApexBio |
50 mg |
EUR 128 |
|
Description: Pentamidine Dihydrochloride(MP601205 dihydrochloride) is an antimicrobial agent. |
 Mizolastine dihydrochloride |
|
B1116-100 |
ApexBio |
100 mg |
EUR 238 |
|
Description: Mizolastine dihydrochloride is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions. |
|
Mizolastine dihydrochloride |
|
B1116-200 |
ApexBio |
200 mg |
EUR 390 |
|
Description: Mizolastine dihydrochloride is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions. |
|
Mizolastine dihydrochloride |
|
B1116-500 |
ApexBio |
500 mg |
EUR 653 |
|
Description: Mizolastine dihydrochloride is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions. |
 IT1t dihydrochloride |
|
B5650-10 |
ApexBio |
10 mg |
EUR 321 |
|
Description: IT1t dihydrochloride is a potent antagonist of CXCR4 with IC50 value of 8.0 nM [1]. C-X-C chemokine receptor type 4 (CXCR4) is an ?-chemokine receptor for chemokine CXCL12. |
|
IT1t dihydrochloride |
|
B5650-100 |
ApexBio |
100 mg |
EUR 1750 |
|
Description: IT1t dihydrochloride is a potent antagonist of CXCR4 with IC50 value of 8.0 nM [1]. C-X-C chemokine receptor type 4 (CXCR4) is an ?-chemokine receptor for chemokine CXCL12. |
|
IT1t dihydrochloride |
|
B5650-25 |
ApexBio |
25 mg |
EUR 592 |
|
Description: IT1t dihydrochloride is a potent antagonist of CXCR4 with IC50 value of 8.0 nM [1]. C-X-C chemokine receptor type 4 (CXCR4) is an ?-chemokine receptor for chemokine CXCL12. |
|
IT1t dihydrochloride |
|
B5650-5 |
ApexBio |
5 mg |
EUR 203 |
|
Description: IT1t dihydrochloride is a potent antagonist of CXCR4 with IC50 value of 8.0 nM [1]. C-X-C chemokine receptor type 4 (CXCR4) is an ?-chemokine receptor for chemokine CXCL12. |
|
IT1t dihydrochloride |
|
B5650-5.1 |
ApexBio |
10 mM (in 1mL DMSO) |
EUR 218 |
|
Description: IT1t dihydrochloride is a potent antagonist of CXCR4 with IC50 value of 8.0 nM [1]. C-X-C chemokine receptor type 4 (CXCR4) is an ?-chemokine receptor for chemokine CXCL12. |
|
IT1t dihydrochloride |
|
B5650-50 |
ApexBio |
50 mg |
EUR 1027 |
|
Description: IT1t dihydrochloride is a potent antagonist of CXCR4 with IC50 value of 8.0 nM [1]. C-X-C chemokine receptor type 4 (CXCR4) is an ?-chemokine receptor for chemokine CXCL12. |
 Cystamine dihydrochloride |
|
B5785-5.1 |
ApexBio |
10 mM (in 1mL DMSO) |
EUR 108 |
|
Cystamine dihydrochloride |
|
B5785-50 |
ApexBio |
50 mg |
EUR 112 |
 Fluphenazine dihydrochloride |
|
B6132-100 |
ApexBio |
100 mg |
EUR 150 |
|
Description: EC50: 1.24 ?MFluphenazine is a dopamine D1 and D2 receptor inhibitor.Dopamine D1 and D2 receptor immunohistochemistry has been used to study the structure of the adult rat arcuate-median eminence complex, particularly in relation to the tubero-infundibular dopamine neurons. |
|
Fluphenazine dihydrochloride |
|
B6132-5.1 |
ApexBio |
10 mM (in 1mL DMSO) |
EUR 168 |
|
Description: EC50: 1.24 ?MFluphenazine is a dopamine D1 and D2 receptor inhibitor.Dopamine D1 and D2 receptor immunohistochemistry has been used to study the structure of the adult rat arcuate-median eminence complex, particularly in relation to the tubero-infundibular dopamine neurons. |
 Dilazep dihydrochloride |
|
B6316-50 |
ApexBio |
50 mg |
EUR 268 |
 Dimaprit dihydrochloride |
|
B6328-100 |
ApexBio |
100 mg |
EUR 268 |
 Naloxonazine dihydrochloride |
|
B6366-10 |
ApexBio |
10 mg |
EUR 221 |
|
Naloxonazine dihydrochloride |
|
B6366-50 |
ApexBio |
50 mg |
EUR 772 |
 Ethambutol dihydrochloride |
|
E005-100G |
TOKU-E |
100 g |
EUR 424 |
|
Ethambutol dihydrochloride |
|
E005-25G |
TOKU-E |
25 g |
EUR 143 |
 Piperazine Dihydrochloride |
|
abx180858-100g |
Abbexa |
100 g |
EUR 230 |
- Shipped within 1-2 weeks.
|
 Pramipexole dihydrochloride |
|
20-abx180860 |
Abbexa |
-
EUR 453.00
-
EUR 230.00
-
EUR 370.00
|
|
- Shipped within 1-2 weeks.
|
|
Vatalanib Dihydrochloride |
|
20-abx076544 |
Abbexa |
|
|
- Shipped within 5-12 working days.
|
 DMPQ Dihydrochloride |
|
20-abx076714 |
Abbexa |
|
|
- Shipped within 5-12 working days.
|
 H89 Dihydrochloride |
|
20-abx076747 |
Abbexa |
|
|
- Shipped within 5-12 working days.
|
 Naftopidil Dihydrochloride |
|
E1KS1387 |
EnoGene |
25mg |
EUR 247 |
 Cefotiam Dihydrochloride |
|
C095-100MG |
TOKU-E |
100 mg |
EUR 232 |
|
Cefotiam Dihydrochloride |
|
C095-50MG |
TOKU-E |
50 mg |
EUR 144 |
 Chlorhexidine Dihydrochloride |
|
C157-25G |
TOKU-E |
25 g |
EUR 185 |
|
Chlorhexidine Dihydrochloride |
|
C157-5G |
TOKU-E |
5 g |
EUR 72 |
 Piribedil dihydrochloride |
|
B6557-10 |
ApexBio |
10 mg |
EUR 139 |
|
Piribedil dihydrochloride |
|
B6557-100 |
ApexBio |
100 mg |
EUR 215 |
The current article outlines and discusses these tips to assist life science researchers publish ethically, in addition to to determine moral journals as readers, authors, and reviewers. We define latest developments in scholarly publishing that we expect will enhance the working surroundings and profession prospects for life scientists. Most prominently, we talk about two key developments. (1) Life scientists at the moment are embracing a preprint tradition main to fast dissemination of research findings. (2) We define steps to overcome the reproducibility disaster. We additionally briefly describe different improvements in scholarly publishing, together with modifications to open entry mandates from funding companies.
)
Histamine (phosphate) 
